CVE-2025-53948 Overview
CVE-2025-53948 is a Double Free vulnerability affecting Sante PACS Server, a medical imaging storage and communication system used in healthcare environments. A remote attacker can exploit this flaw by sending a specially crafted HL7 (Health Level 7) message to the server, causing the main thread to crash and resulting in a denial-of-service condition. The vulnerability is particularly concerning because it requires no authentication to exploit and forces administrators to manually restart the application to restore service.
Critical Impact
Unauthenticated remote attackers can crash critical healthcare imaging infrastructure, disrupting medical operations and potentially impacting patient care through service unavailability.
Affected Products
- Santesoft Sante PACS Server (all vulnerable versions)
Discovery Timeline
- 2025-08-18 - CVE-2025-53948 published to NVD
- 2025-10-17 - Last updated in NVD database
Technical Details for CVE-2025-53948
Vulnerability Analysis
This vulnerability stems from a Double Free memory corruption issue (CWE-415) in the Sante PACS Server's HL7 message processing functionality. When the server receives a maliciously crafted HL7 message over the network, improper memory management causes the same memory location to be freed twice. This memory corruption leads to undefined behavior, ultimately crashing the main application thread.
The impact is limited to availability—the attack does not allow information disclosure or data modification. However, the vulnerability is network-accessible without any authentication requirements, making it trivially exploitable by any attacker with network access to the HL7 interface. Healthcare organizations relying on Sante PACS Server for medical imaging workflows face significant operational risks, as the service disruption requires manual intervention to restore.
Root Cause
The root cause is a Double Free condition (CWE-415) in the HL7 message parsing logic. When processing certain malformed HL7 message structures, the application incorrectly attempts to deallocate the same memory block multiple times. This occurs because the code path does not properly track whether a memory buffer has already been freed, leading to corruption of the heap memory management structures and subsequent application crash.
Attack Vector
The attack is conducted remotely over the network by connecting to the Sante PACS Server's HL7 interface and transmitting a specially crafted HL7 message. The HL7 protocol is commonly used for healthcare data exchange and typically operates on TCP port 2575 or similar configured ports. Since the vulnerability requires no authentication, any attacker with network access to the HL7 service port can trigger the denial-of-service condition.
The attack flow involves:
- Establishing a TCP connection to the Sante PACS Server's HL7 listening port
- Sending a malformed HL7 message containing structures that trigger the double free condition
- The server's main thread crashes upon processing the malicious message
- Service becomes unavailable until manual restart by an administrator
See the CISA Medical Advisory ICSMA-25-224-01 for technical details regarding the exploitation mechanism and recommended countermeasures.
Detection Methods for CVE-2025-53948
Indicators of Compromise
- Unexpected Sante PACS Server service terminations or crashes requiring manual restart
- Unusual or malformed HL7 messages in server logs prior to service crashes
- Repeated connection attempts to the HL7 service port from unexpected sources
- Memory corruption or access violation errors in application crash dumps
Detection Strategies
- Monitor Sante PACS Server process availability and alert on unexpected terminations
- Implement network-level inspection of HL7 traffic for malformed message structures
- Deploy intrusion detection rules to identify anomalous HL7 message patterns targeting the server
- Configure application-level logging to capture HL7 message parsing errors and exceptions
Monitoring Recommendations
- Enable verbose logging on the Sante PACS Server to capture HL7 message processing events
- Implement automated service health monitoring with immediate alerting on service failures
- Review network traffic to HL7 ports for unusual volumes or patterns that may indicate exploitation attempts
- Correlate Sante PACS Server crash events with network connection logs to identify potential attack sources
How to Mitigate CVE-2025-53948
Immediate Actions Required
- Review the CISA Medical Advisory ICSMA-25-224-01 for vendor-recommended actions
- Restrict network access to the HL7 service port to only trusted healthcare systems and networks
- Implement network segmentation to isolate the Sante PACS Server from untrusted network segments
- Deploy a firewall or access control list to limit connections to the HL7 interface
- Monitor for available patches from Santesoft and apply as soon as released
Patch Information
Consult the CISA Medical Advisory ICSMA-25-224-01 for the latest patch availability and remediation guidance from Santesoft. Organizations should prioritize applying vendor-supplied patches as they become available.
Workarounds
- Implement strict network access controls to limit HL7 interface exposure to trusted sources only
- Deploy a reverse proxy or application-level gateway capable of inspecting and filtering HL7 traffic
- Consider disabling the HL7 interface temporarily if not operationally required until a patch is available
- Implement automated service restart mechanisms to minimize downtime in the event of exploitation
# Example firewall rule to restrict HL7 port access (adjust port number as needed)
# Allow only trusted healthcare network to access HL7 service
iptables -A INPUT -p tcp --dport 2575 -s 10.10.0.0/16 -j ACCEPT
iptables -A INPUT -p tcp --dport 2575 -j DROP
Disclaimer: This content was generated using AI. While we strive for accuracy, please verify critical information with official sources.

