The SentinelOne Annual Threat Report - A Defenders Guide from the FrontlinesThe SentinelOne Annual Threat ReportGet the Report
Experiencing a Breach?Blog
Get StartedContact Us
SentinelOne
  • Platform
    Platform Overview
    • Singularity Platform
      Welcome to Integrated Enterprise Security
    • AI for Security
      Leading the Way in AI-Powered Security Solutions
    • Securing AI
      Accelerate AI Adoption with Secure AI Tools, Apps, and Agents.
    • How It Works
      The Singularity XDR Difference
    • Singularity Marketplace
      One-Click Integrations to Unlock the Power of XDR
    • Pricing & Packaging
      Comparisons and Guidance at a Glance
    Data & AI
    • Purple AI
      Accelerate SecOps with Generative AI
    • Singularity Hyperautomation
      Easily Automate Security Processes
    • AI-SIEM
      The AI SIEM for the Autonomous SOC
    • AI Data Pipelines
      Security Data Pipeline for AI SIEM and Data Optimization
    • Singularity Data Lake
      AI-Powered, Unified Data Lake
    • Singularity Data Lake for Log Analytics
      Seamlessly Ingest Data from On-Prem, Cloud or Hybrid Environments
    Endpoint Security
    • Singularity Endpoint
      Autonomous Prevention, Detection, and Response
    • Singularity XDR
      Native & Open Protection, Detection, and Response
    • Singularity RemoteOps Forensics
      Orchestrate Forensics at Scale
    • Singularity Threat Intelligence
      Comprehensive Adversary Intelligence
    • Singularity Vulnerability Management
      Application & OS Vulnerability Management
    • Singularity Identity
      Identity Threat Detection and Response
    Cloud Security
    • Singularity Cloud Security
      Block Attacks with an AI-Powered CNAPP
    • Singularity Cloud Native Security
      Secure Cloud and Development Resources
    • Singularity Cloud Workload Security
      Real-Time Cloud Workload Protection Platform
    • Singularity Cloud Data Security
      AI-Powered Threat Detection for Cloud Storage
    • Singularity Cloud Security Posture Management
      Detect and Remediate Cloud Misconfigurations
    Securing AI
    • Prompt Security
      Secure AI Tools Across Your Enterprise
  • Why SentinelOne?
    Why SentinelOne?
    • Why SentinelOne?
      Cybersecurity Built for What’s Next
    • Our Customers
      Trusted by the World’s Leading Enterprises
    • Industry Recognition
      Tested and Proven by the Experts
    • About Us
      The Industry Leader in Autonomous Cybersecurity
    Compare SentinelOne
    • Arctic Wolf
    • Broadcom
    • CrowdStrike
    • Cybereason
    • Microsoft
    • Palo Alto Networks
    • Sophos
    • Splunk
    • Trellix
    • Trend Micro
    • Wiz
    Verticals
    • Energy
    • Federal Government
    • Finance
    • Healthcare
    • Higher Education
    • K-12 Education
    • Manufacturing
    • Retail
    • State and Local Government
  • Services
    Managed Services
    • Managed Services Overview
      Wayfinder Threat Detection & Response
    • Threat Hunting
      World-Class Expertise and Threat Intelligence
    • Managed Detection & Response
      24/7/365 Expert MDR Across Your Entire Environment
    • Incident Readiness & Response
      DFIR, Breach Readiness, & Compromise Assessments
    Support, Deployment, & Health
    • Technical Account Management
      Customer Success with Personalized Service
    • SentinelOne GO
      Guided Onboarding & Deployment Advisory
    • SentinelOne University
      Live and On-Demand Training
    • Services Overview
      Comprehensive Solutions for Seamless Security Operations
    • SentinelOne Community
      Community Login
  • Partners
    Our Network
    • MSSP Partners
      Succeed Faster with SentinelOne
    • Singularity Marketplace
      Extend the Power of S1 Technology
    • Cyber Risk Partners
      Enlist Pro Response and Advisory Teams
    • Technology Alliances
      Integrated, Enterprise-Scale Solutions
    • SentinelOne for AWS
      Hosted in AWS Regions Around the World
    • Channel Partners
      Deliver the Right Solutions, Together
    • SentinelOne for Google Cloud
      Unified, Autonomous Security Giving Defenders the Advantage at Global Scale
    • Partner Locator
      Your Go-to Source for Our Top Partners in Your Region
    Partner Portal→
  • Resources
    Resource Center
    • Case Studies
    • Data Sheets
    • eBooks
    • Reports
    • Videos
    • Webinars
    • Whitepapers
    • Events
    View All Resources→
    Blog
    • Feature Spotlight
    • For CISO/CIO
    • From the Front Lines
    • Identity
    • Cloud
    • macOS
    • SentinelOne Blog
    Blog→
    Tech Resources
    • SentinelLABS
    • Ransomware Anthology
    • Cybersecurity 101
  • About
    About SentinelOne
    • About SentinelOne
      The Industry Leader in Cybersecurity
    • Investor Relations
      Financial Information & Events
    • SentinelLABS
      Threat Research for the Modern Threat Hunter
    • Careers
      The Latest Job Opportunities
    • Press & News
      Company Announcements
    • Cybersecurity Blog
      The Latest Cybersecurity Threats, News, & More
    • FAQ
      Get Answers to Our Most Frequently Asked Questions
    • DataSet
      The Live Data Platform
    • S Foundation
      Securing a Safer Future for All
    • S Ventures
      Investing in the Next Generation of Security, Data and AI
  • Pricing
Get StartedContact Us
CVE Vulnerability Database
Vulnerability Database/CVE-2025-3481

CVE-2025-3481: MedDream PACS Server RCE Vulnerability

CVE-2025-3481 is a stack-based buffer overflow RCE vulnerability in MedDream PACS Server that allows unauthenticated attackers to execute arbitrary code. This article covers technical details, affected versions, and mitigation.

Published: May 11, 2026

CVE-2025-3481 Overview

CVE-2025-3481 is a stack-based buffer overflow [CWE-121] in MedDream PACS Server that enables arbitrary code execution through malicious DICOM file parsing. The flaw exists in the routine that copies user-supplied data into a fixed-length stack buffer without validating its length. Successful exploitation grants code execution in the context of the PACS service account. The issue was reported through the Zero Day Initiative as ZDI-CAN-25827 and disclosed publicly as ZDI-25-245. While the CVSS attack vector is local, the trigger is a crafted DICOM file, meaning any workflow that ingests untrusted imaging studies can deliver the payload.

Critical Impact

Remote attackers can execute arbitrary code on MedDream PACS Server installations by delivering a malicious DICOM file, compromising medical imaging infrastructure and patient data.

Affected Products

  • MedDream PACS Server (Premium edition)
  • Installations parsing DICOM files prior to the vendor patch
  • Healthcare environments accepting external DICOM uploads

Discovery Timeline

  • 2025-05-22 - CVE-2025-3481 published to NVD
  • 2025-07-11 - Last updated in NVD database

Technical Details for CVE-2025-3481

Vulnerability Analysis

The vulnerability resides in the DICOM file parser of MedDream PACS Server. Digital Imaging and Communications in Medicine (DICOM) is the standard format for medical imaging data. When the server processes a DICOM file, it reads attacker-controlled fields and copies them into a stack-allocated buffer of fixed size. The parser does not verify that the source length fits the destination buffer before performing the copy.

An attacker who can place or transmit a crafted DICOM file to the server triggers a stack buffer overflow during parsing. The overflow corrupts adjacent stack memory, including saved return addresses and structured exception handlers. Successful exploitation yields arbitrary code execution under the service account that runs the PACS process. In typical deployments this account has broad access to imaging archives, study databases, and integrated hospital systems.

Root Cause

The root cause is missing bounds validation [CWE-121] prior to a memory copy operation on user-controlled DICOM tag data. The parser trusts length or terminator values present in the file and writes past the end of a fixed-size stack buffer.

Attack Vector

Exploitation requires the target server to parse the malicious DICOM file. Delivery paths include DICOM upload endpoints, file shares monitored by the PACS, and any modality or workstation that routes studies to the server. User interaction is required to process the file, as reflected in the CVSS vector. Refer to the Zero Day Initiative Advisory ZDI-25-245 for technical specifics.

// No verified proof-of-concept code is publicly available.
// See ZDI-25-245 for vendor and researcher technical details.

Detection Methods for CVE-2025-3481

Indicators of Compromise

  • Unexpected crashes or restarts of the MedDream PACS Server process during DICOM ingestion
  • DICOM files containing oversized tag values that exceed standard field length expectations
  • Child processes spawned by the PACS service account, particularly command interpreters or scripting engines
  • Outbound network connections initiated by the PACS service to non-imaging endpoints

Detection Strategies

  • Inspect inbound DICOM files for malformed or excessively long attribute values prior to ingestion
  • Monitor the PACS service process for memory access violations and abnormal termination events
  • Hunt for anomalous process trees originating from the MedDream service binary
  • Correlate Windows Error Reporting and application crash logs with DICOM upload activity

Monitoring Recommendations

  • Enable verbose logging on DICOM receive endpoints and retain files for forensic review
  • Forward PACS host telemetry, including process creation and module load events, to a centralized analytics platform
  • Alert on first-time binaries or scripts executed by the PACS service account

How to Mitigate CVE-2025-3481

Immediate Actions Required

  • Restrict DICOM ingestion to authenticated peers on trusted network segments only
  • Apply the vendor-supplied patch from MedDream as soon as it is available
  • Run the PACS service under a least-privilege account with no interactive logon rights
  • Isolate the PACS host from general-purpose user workstations and the public internet

Patch Information

Consult the Zero Day Initiative Advisory ZDI-25-245 and the MedDream vendor support channel for the fixed release of PACS Server Premium. Update all instances of the server, including failover and disaster recovery nodes.

Workarounds

  • Place a DICOM-aware proxy or gateway in front of the PACS to validate file structure before forwarding
  • Disable any unauthenticated DICOM listeners and enforce TLS with peer certificate validation
  • Apply host-based exploit mitigations such as Data Execution Prevention and Control Flow Guard on the PACS host
bash
# Example: restrict DICOM port 104 to known modality IPs on Windows
netsh advfirewall firewall add rule name="PACS-DICOM-Allowlist" \
  dir=in action=allow protocol=TCP localport=104 \
  remoteip=10.0.0.10,10.0.0.11,10.0.0.12
netsh advfirewall firewall add rule name="PACS-DICOM-DenyAll" \
  dir=in action=block protocol=TCP localport=104

Disclaimer: This content was generated using AI. While we strive for accuracy, please verify critical information with official sources.

  • Vulnerability Details
  • TypeRCE

  • Vendor/TechMeddream Pacs Server

  • SeverityHIGH

  • CVSS Score7.8

  • EPSS Probability0.48%

  • Known ExploitedNo
  • CVSS Vector
  • CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H
  • Impact Assessment
  • ConfidentialityLow
  • IntegrityHigh
  • AvailabilityHigh
  • CWE References
  • CWE-121
  • Technical References
  • Zero Day Initiative Advisory ZDI-25-245
  • Related CVEs
  • CVE-2025-3484: Meddream PACS Server RCE Vulnerability

  • CVE-2025-3483: MedDream PACS Server RCE Vulnerability

  • CVE-2025-3482: Meddream PACS Server RCE Vulnerability

  • CVE-2025-27724: Meddream PACS Privilege Escalation Flaw
Default Legacy - Prefooter | Experience the World’s Most Advanced Cybersecurity Platform

Experience the World’s Most Advanced Cybersecurity Platform

See how our intelligent, autonomous cybersecurity platform can protect your organization now and into the future.

Try SentinelOne
  • Get Started
  • Get a Demo
  • Product Tour
  • Why SentinelOne
  • Pricing & Packaging
  • FAQ
  • Contact
  • Contact Us
  • Customer Support
  • SentinelOne Status
  • Language
  • Platform
  • Singularity Platform
  • Singularity Endpoint
  • Singularity Cloud
  • Singularity AI-SIEM
  • Singularity Identity
  • Singularity Marketplace
  • Purple AI
  • Services
  • Wayfinder TDR
  • SentinelOne GO
  • Technical Account Management
  • Support Services
  • Verticals
  • Energy
  • Federal Government
  • Finance
  • Healthcare
  • Higher Education
  • K-12 Education
  • Manufacturing
  • Retail
  • State and Local Government
  • Cybersecurity for SMB
  • Resources
  • Blog
  • Labs
  • Case Studies
  • Videos
  • Product Tours
  • Events
  • Cybersecurity 101
  • eBooks
  • Webinars
  • Whitepapers
  • Press
  • News
  • Ransomware Anthology
  • Company
  • About Us
  • Our Customers
  • Careers
  • Partners
  • Legal & Compliance
  • Security & Compliance
  • Investor Relations
  • S Foundation
  • S Ventures

©2026 SentinelOne, All Rights Reserved.

Privacy Notice Terms of Use

English